Dengue NS1 a rapid immunochromatographic test for the qualitative detection of dengue virus NS1 antigen in human serum/plasma/whole blood for early diagnosis of acute infection. Dengue virus belongs to Flaviviridae family, common in tropical and sub-tropical regions, which is found in four distinct serotypes (1, 2, 3 and 4). Dengue fever is transmitted by mosquitoes, of the species Aedes aegypti and Aedes albopictus. Primary dengue infection results mostly in a self-limiting mild to high fever, while secondary infection is more common and potentially fatal resulting in severe conditions like Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). The following table gives the duration for detectable rise in NS1 antigen in blood in cases of primary and secondary infections:
|Ag||Primary Infection||Secondary Infection|
|NS1||1-9 days upto 15 days||1-9 days|
NS1 antigen appears from day 1 in blood and helps in early diagnosis which reduces risks of complications.
The unreacted complexes move even further and are immobilized at the control region “C” and form a pink/purple colored band. Absence of control line “C” indicates an INVALID TEST.